Schoeberl, B., Pace, E.A, Fitzgerald, J.B., Harms, B.D., Xu, L., Nie, L., Linggi, B., Kalra, A., Paragas, V., Bukhalid, R., Grantcharova, V., Kohli, N., West, K.A., Leszczyniecka, M., Feldhaus, M.J., Kudla, A.J., and Ulrik. B. Nielsen. Therapeutically Targeting ErbB3: A Key Node in Ligand-Induced Activation of the ErbB Receptor-PI3K Axis. 2009. Science Signaling. 30 June 2009; Volume 2, Issue 77, ra31.

Chen, W.W., Schoeberl, B., Jasper, P.J., Niepel, M., Nielsen, U.B., Lauffenburger, D.A., and Peter K Sorger. Input-Output Behavior of ErbB Signaling Pathways as Revealed by a Mass Action Model Trained Against Dynamic Data. 2009. Molecular Systems Biology. 20 January 2009;doi:10.1038/msb.2008.74.

Pollard, L.C., Murray, J., Moody, M., Stewart, E.J., and Ernest H.S. Choy.  A Randomised, Double-blind, Placebo-controlled Trial of a Recombinant Version of Human Alpha-fetoprotein (MM-093) in Patients with Active Rheumatoid Arthritis. 2007. Annals of the Rheumatic Diseases. May;66(5):687-9.

Schoeberl, B., Nielsen, U.B., and Riccardo Paxson.  Model-based Design Approaches in Drug Discovery: A Parallel to Traditional Engineering Approaches  2006. IBM Journal of Research and Development. November;50(6):645.

Wolf-Yadlin, Alejandro, Kumar, Neil, Zhang, Yi, Hautaniemi, Sampsa, Zaman, Muhammad, Kim, Hyung-Do, Grantcharova, Viara, Lauffenburger, Douglas A., and Forest M. White.  Effects of HER2 Overexpression on Cell Signaling Networks Governing Proliferation and Migration 2006. Molecular Systems Biology. October;2(54).

Fitzgerald, J.B., Schoeberl, B., Nielsen, U.B., and Peter K. Sorger.  Systems Biology and Combination Therapy in the Quest for Clinical Efficacy  2006. Nature Chemical Biology. September;2(9):458-66.

Janes, K.A., Gaudet, S., Albeck, J.G., Nielsen, U.B., Lauffenburger, D.A., and Peter K. Sorger.  The Response of Human Epithelial Cells to TNF Involves an Inducible  Autocrine Cascade.  2006. Cell. March;24(124):1225-1239.

Nielsen, U.B. and Birgit Schoeberl. Using Computational Modeling to Drive the Development of Targeted Therapeutics. 2005. IDrugs. Oct;8(10):822-6.

Gaudet, S., Janes, K.A., Albeck, J.G., Pace, E.A., Lauffenburger, D.A., and Peter K. Sorger. A Compendium of Signals and Responses Triggered by Prodeath and Prosurvival Cytokines. 2005. Mol Cell Proteomics.

Hornberg JJ, Binder B, Bruggeman FJ, Schoeberl B, Heinrich R., and Hans V. Westerhoff. Control of MAPK Signalling: from Complexity to What Really Matters. 2005. Oncogene: 24(36):5533-42.

Nielsen, U.B. and Bernhard H. Geierstanger. Multiplexed Sandwich Assays in Microarray Format. 2004. Journal of Immunological Methods: 290(1-2):170-120.

Parker, M.H., Birck-Wilson, E., Allard, G. Masiello, N., Day, M., Murphy, K.P., Paragas, V., Silver, S., and Mark D. Moody. Purification and Characterization of a Recombinant Version of Human alpha-fetoprotein Expressed in the Milk of Transgenic Goats. 2004. Protein Expression & Purification: 38(2): 184-195.

Nielsen, U.B., Cardone, M.H., Sinskey, A.J., MacBeath, G., and Peter K. Sorger. Profiling Receptor Tyrosine Kinase Activation By Using Ab Microarrays. 2003. PNAS: 100(16):9330-9335.

Schoeberl, B., Eichler-Jonsson, C., Dieter Gilles, E., and Gertraud Müller. Computational Modeling of the Dynamics of the MAP Kinase Cascade Activated by Surface and Internalized EGF Receptors 2002 Nature Biotechnology: 20.

[ back to top ]